Can you take CBD oil with other medications and drugs?

The different medications and supplements that we take have the potential to interact with other medications and supplements. Even herbal products can interact with things you’re taking. CBD is a component of the cannabis plant that can be very beneficial for a variety of health issues. However, there are precautions that you should take when you consume CBD. This is a very safe substance that children, adults and pets can use to improve their overall health. Let’s take a closer look at the different interactions that can occur with CBD and some commonly used medications.
CBD Interactions
The process of metabolism of CBD is usually where the problems will occur. When your body is only taking CBD, your body can process it normally. When the CBD interacts with other things, it can stay in your system too long, or it can be flushed out of your system too quickly. The same thing can happen with the other drugs in your system. This can lead to a deadly level of concentration in your body. CBD has shown to affect a number of different health conditions thanks to its effect on the endocannabinoid system.

Interactions with Antidepressants
CBD is a natural supplement that you can use to improve your mood. People who deal with anxiety or depression know how debilitating these mental conditions can be. A lot of patients are already on a prescription antidepressant. There is a possibility that CBD and these medications will interact. It is rare for an SSRI to interact with CBD, but there is a slight risk of hypomania. This would be more prevalent in someone who is dealing with bipolar disorder.

Blood Thinners
Most patients that are taking blood thinners can also take CBD with no dangerous side effects. However, there is a slightly increased risk of the amount of blood thinners in the body building up to a level that was not intended by the prescribing doctor. Most patients on blood thinners will be frequently monitored for their clotting ability and the levels of the medication in their blood. After speaking with your doctor, you can use this testing as a way to confirm that your CBD is not a problem.

Seizure Medications
CBD is showing a lot of promise when it comes to treating seizure disorders. There has even been a prescription CBD medication approved by the FDA for the treatment of epilepsy. Frequent use of CBD has the potential to increase levels of Clobazam in the body. This anti-seizure medication is often prescribed to children. This is a category of drugs that interacts with an enzymatic system in our bodies that processes our medications and supplements.

Cold Medications
Any of the over-the-counter medications that are sold as relief-products for the common cold and flu can interact with CBD. While it’s not life-threatening, CBD can interact with with Nyquil or other cold medications, causing extreme fatigue and drowsiness. If you’re really under the weather, you might want to limit your use of CBD while you cope with your cold symptoms. However, CBD does have the potential to boost your immune function. You’ll have to weigh your options.

We have a cytochrome P-450 enzyme system in the body that is largely responsible for metabolizing as much as ninety percent of the drugs that we are consuming each day. When these medications are broken down into simpler substances, our bodies will benefit. CBD can cause this enzyme system to become inactive for the time being. The body will have a much harder time processing what you put into it. Make sure that you speak with your doctor about potential interactions before you starting taking anything new, including CBD.

Alex Malkin

Editor-in-chief at

Expert in healthy lifestyle and food supplements with a deep knowledge in CBD (Cannabidiol).

All opinions expressed on USDR are those of the author and not necessarily those of US Daily Review.