Emerging Trends in Biotechnology

Following the advances in technology developments, the biotechnology industry has also experienced significant changes, including synthetic plant biology, engineered microbial consortia, which is geared towards clinical translation of bio fabrication. The following are some of the fantastic emerging trends in biotechnology:

Physiology-on-a-chip

Biotechnology has developed organs-on-chips technology, which is used in the study of the behavior of organs and cells outside the human body following their customizability, miniature, and capability to be combined. The on-chip approaches have become so popular that their concept has been extended to all vivo systems. This implies that the method is not just for devices intending to recapitulate the behavior of specific organ-associated tissues. The approach is used to offer a micro-scale platform for understanding how living organisms operate.

Additionally, physiology-on-a-chip has been used to study the mechanical loading of joints, aging, and thrombosis. The implication, in this case, is that biotechnology has made it easy for health practitioners to understand the operation of living organisms for customized health provision solutions.

Immunotherapy and Exosomes in Cancer Nanomedicine

Yet there is no cure for cancer, but there have been various developments in R&D of the cancer vaccines, drugs, and therapies. Among such events are exosomes. It encompasses cell-driven and versatile nanovesicles having the ability to overcome biological barriers and lead to the production of reasonable amounts of bioactive molecules to particular recipient tissues. This approach has developed fantastic strategies in cancer immunotherapy and drug delivery.

The biotechnology applied in cancer treatment encompasses bioengineered exosomes that are deployed in particular areas of the body infected with cancer cells. The exosomes are used to deliver potent tumoricidal drugs that contain chemotherapeutic and siRNAs compounds to the affected parts of the body.

Moreover, biotechnology has been used to encourage progress in the development of therapeutic cancer vaccines based on the reports obtained from the early stages of clinical trials of the drugs.

Genome Editing

This includes CRISPR, which is a technology developed to manipulate the genomes of a living organism. The technology has been made easily customizable and easy to implement. The approach has been used in editing the genomes of food crops, pests, cyanobacteria, tumor cells alongside other industrially relevant microorganisms.

The CRISPR/Cas system has been improved to expand its utility beyond the microbial defense mechanism. Through this biotechnology, Cas9 can be engineered to create unique proteins. It is also used in the modification of a specific DNA sequence. CRISPR has also led to the development of other Cas variants, including Cas12a for editing genomes, Cas13 essential for manipulation of RNA, and Cas14 that is associated with the improvements in molecular discovery.

Neuroscience

The human brain is an intricate and complex organ in the human body. Researchers have taken decades to study how the human brain works. However, understanding this isn’t easy. Following this, researchers have invested in neuroscience to understand the mechanism of the brain. This, therefore, implies that the neuroscience industry is growing outside and within the biotechnology sector. Some of the developments in neuroscience include increased research in mapping brain techniques for understanding the functionality of the human brain. All the developments in the neuroscience sector strive to improve the understanding of how the brain works and treatment of brain-related diseases like depression, anxiety and mood disorders, PTSD, and Alzheimer’s disease.

Bionic Organisms

Bionic organisms may seem like science fiction, but it is a futuristic way aimed at describing a living organism having some inorganic components designed to alter or improve its functionality. The technology includes microchipping a pet to make it bionic.

Over the past years, there has been a publication about biohybrid yeast and bionic mushroom, which are regarded as organisms with nanomaterial modifications. Such modification intends to harvest light energy in different ways for varying purposes. The yeast relies on nanoparticles on the cellular surface as artificial photoreceptors that provide energy for chemical reactions, whereas bionic mushroom is artificially photosynthetic, it uses cyanobacteria to absorb light energy.   

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